Dr Simon MacDonald

Dr MacDonald graduated from Oxford University before junior doctor training in London (Hammersmith, Queens Square, Whittington/UCL, Guys and St Thomas’ Hospitals). Formal adult cardiology training in the Oxford Postgraduate Deanery in the UK followed with additional training in paediatric cardiology and congenital interventional training fellowships at The Heart Hospital, London, and the Policlinico San Donato, Milan. He has over 20 years of experience of medicine and cardiology. He obtained a DPhil/ PhD in heart developmental genetics as a Wellcome Trust CVRI Prize Clinical Fellow during training.

His first substantive consultant post was in Adult Congenital Heart Disease and he also became Honorary Senior Lecturer in Cardiology at Glenfield Hospital, Leicester, before moving to Barts Heart Centre, London in 2019 for greater structural and ACHD experience.
He moved out to work at University Hospital of Wales, Cardiff in 2021, also becoming a Honorary Consultant at University Hospitals of Bristol NHS Foundation Trust.

Adult congenital heart disease, congenital and structural intervention, pulmonary hypertension in congenital heart disease, outcomes research in ACHD, general adult cardiology

Congenital and structural interventions and their outcomes, device registries, ACHD outcomes, evidence based cardiology

BSc(MedSci)(Pathol)Hons)(Edin) 1994
BMBCh (Oxon) 1997
MRCP(London) 2000
DPhil (Oxon) 2007
FRCP(London) 2018

Year of first medical qualification: 1997

British Cardiovascular Society (BCS)
European Society of Cardiology (ESC)
Fellow of Royal College of Physicians (London)(FRCP)
British Cardiovascular Intervention Society (BCIS)
European Association of Percutaneous Cardiovascular Interventions (EAPCI)
Paediatric/Congenital Interventional Early Career Society (PICES)
British Society Echocardiography (BSE)
British Medical Association (BMA)

Dr MacDonalds enjoys cycling, running and taking his young children swimming, as well as playing traditional musical instruments.

He is medical lead for a charity offering heart screening for young Welsh sports people.

Consultant Cardiologist at Cardiff and Vale; University Hospitals Bristol

Wellcome Trust CVRI Prize Junior Fellowship, Oxford University 2004-7
European Society of Cardiology (ESC) Young Investigator Award 2007
British Junior Cardiac Association International Research Awards Winner 2007
British Cardiovascular Society (BCS) Young Investigator Award 2008
Post doctoral JRF at Oxford following DPhil (Emanoel Lee JRF) 2008
HCA International Travelling Fellowship
UCL/ Caius College Cambridge Berkeley Fellowship 2010.
NHS Innovation Challenge Prize- National Finalist 2013

Approximately 2000 catheter procedures performed without significant mortality nor morbidity, regularly auditing practice and outcomes. Dr MacDonald keeps up to date by attending national and international conferences, reviewing for key cardiology journals, and being involved in studies.
TOE/Echo accredited. 
Dr MacDonald empowers patients to make the best informed decisions about their treatment options and care.

Online list of publications available at www. orcid.org/0000-0001-9940-1186 

Over 40 publications and book chapters.
Selected publications:
- Neijenhuis RML, MacDonald ST, Zemrak P, Mertens BJA, Dinsdale A, Hunter A, Walker NL,
Swan L, Reddy S, Rotmans JI, Jukema JW, Jongbloed MRM, Veldtman GR, Egorova AD (2024). Effect of sodium-glucose cotransporter 2 inhibitors in adults with congenital heart disease. JACC; 83: 1403-1414

MacDonald ST, Bhan A, Khambadkone S, Mullen M (2023). Percutaneous heart valves
demonstrating long-term durability: a case series of Melody valves in the pulmonary position lasting up to 19 years. Catheter Cardiovasc Interv; 101: 401-6.

Lewis RA, Billings CG, Bolger A, Bowater S, Charalampopoulos A, Clift P, Elliot CA, English K,
Hamilton N, Hill C, Hurdman J, Jenkins PJ, Johns C, MacDonald S, Oliver J, Papaioannou V,
Rajaram S, Sabroe I, Swift AJ, Thompson AAR, Kiely DG, Condliffe R (2020). Partial anomalous
pulmonary venous drainage in patients presenting with suspected pulmonary hypertension: A series of 90 patients from the ASPIRE registry. Respirology; 25: 1066-72.

Dimopoulos K, Condliffe R, Tulloh R, Clift P, Alonso-Gonzalez R, Bedair R, Chung NAY,
Coghlan G, Fitzsimmon S, Frigiola A, Howard L, Jenkins P, Kenny D, Li W, MacDonald ST,
McCabe C, Oliver JJ, Spence M, Szantho GV, von Klemperer K, Wilson DG, Wort SJ (2018).
Echocardiographic screening for pulmonary hypertension in adults with congenital heart disease: JACC review topic of the week. JACC; 72: 2778-2788.

Hildick-Smith D, Williams T, McCarthy P, Melikian N, Monaghan M, Spence M, MacDonald ST, Duke A, Kovac J, McGregor A, Hilling-Smith R, Gomes A, Thomson C, Mullen M, Morrison L (2017). Occlutech percutaneous patent foramen ovale closure: safety and efficacy registry (OPPOSE) Int J Cardiol; 245: 99-104.

MacDonald ST, Taylor AM, O’Leary J, Walker F (2013). Acquired Fontan Physiology secondary
to acute mechanical tricuspid valve failure in a patient with massive right heart enlargement and Ebstein’s anomaly. Circulation; 128: e218-219.

MacDonald ST, Bamforth SD, Braganca J, Chiann-Mun Chen, Farthing CR, Franklyn A,
Broadbent C, Schneider J, Schwartz R, Bhattacharya S (2013). A cell-autonomous role of Cited2 in controlling myocardial and coronary vascular development. Eur Heart J; 34: 2557-65.

MacDonald ST, Daniels MJ, Ormerod OJ (2013). Initial use of the new GORE® Septal Occluder
in patent foramen ovale closure- implantation and preliminary results. Catheter Cardiovasc Interv; 81: 660-5.

Butera G, Castaldi B, MacDonald ST (2012). Over-the-wire-technique device implantation.
Catheter Cardiovasc Interv; 80: 485-92.

Butera G, Hassan E, MacDonald ST (2012). Telescopic catheter in long sheath and parallel to a stiff guide wire technique for complex pulmonary anatomy. Catheter Cardiovasc Interv;80: 673-7.

MacDonald ST, Carminati M, Butera G (2011). Percutaneous implantation of an Edwards SAPIEN valve in a failing pulmonary bioprosthesis in palliated Tetralogy of Fallot. Eur Heart J; 32: 1534.

MacDonald ST, Newton J, Ormerod (2011). Intracardiac echocardiography off piste- Closure of the left atrial appendage using ICE and local anaesthesia. Catheter Cardiovasc Interv; 77: 124-7.

MacDonald ST, Chessa M, Carminati M (2010). Managing adults with congenital heart disease in the catheterization laboratory: State of the art. Expert Rev Cardiovasc Ther; 8: 1741-52.